Effect of Solanum nudum steroids on uninfected and Plasmodium falciparum-infected erythrocytes

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Effect of Solanum nudum steroids on uninfected and Plasmodium falciparum-infected erythrocytes.

Steroids from Solanum nudum (SNs) have demonstrated antiplasmodial activity against erythrocytic stages of the Plasmodium falciparum strain FCB-2. It is well known that steroids can alter the membrane function of erythrocytes. Thus, we assessed alterations in the membranes of uninfected red blood cells, the parasite invasiveness and the solute-induced lysis of parasitised red blood cells (pRBCs...

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ژورنال

عنوان ژورنال: Memórias do Instituto Oswaldo Cruz

سال: 2009

ISSN: 0074-0276

DOI: 10.1590/s0074-02762009000500003